Do you believe in the philosophy of "never give up" or does it sometimes make sense to abandon a goal?

I think if you set a reasonable goal and thought it out, there should never be a reason to give up short of some sort of catastrophe. If you had a health issue that rendered a goal impossible, then of course you'd reconsider that goal. but hardship alone...never a reason. Edison failed 29,000 times to invent the lightbulb.